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Expression and potential regulatory mechanism of cellular senescence-related genes in Alzheimer’s disease based on single-cell and bulk RNA datasets

21 May 2025

Abstract excerpt

Introduction Alzheimer’s disease (AD) is the most common cause of dementia in the elderly. However, the particular cause of AD development has not been fully elucidated. Currently, cellular senescence is recognized as a contributing factor to the aging process and age-related diseases. Methods The present study aimed to identify the hinge of regulatory factors in dysfunctional cellular senescence genes in AD via...

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Share to Epigenetics and DNA Methylation
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PMID: 40470298
DOI: 10.3389/fnins.2025.1595847

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