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Integrative Analysis of Left Ventricle and Epicardial Adipose Tissue Identifies SDHA and OGDH as Candidate Targets for Ischemic Heart Disease

2025-09-20

Abstract excerpt

Ischemic heart disease (IHD) involves coordinated molecular changes across heart, yet their interplay remains poorly understood. Here, we investigated transcriptomic alterations in two heart tissue subtypes, left ventricle (LV) and epicardial adipose tissue (EAT), from age- and BMI-matched healthy and IHD individuals, including both diabetic and non-diabetic patients. We performed transcriptomic profiling and syst...

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Literature Corpus work
d20eb657-9120-58ab-8106-4f94eb184fc5
DOI
10.1101/2025.09.17.676232
Open publication

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Integrative Analysis of Left Ventricle and Epicardial Adipose Tissue Identifies SDHA and OGDH as Candidate Targets for Ischemic Heart DiseaseDOI 10.1101/2025.09.17.676232
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