Article

<i>APOE4</i>and Infectious Diseases Jointly Contribute to Brain Glucose Hypometabolism, a Biomarker of Alzheimer’s Pathology: New Findings from the ADNI

2024-09-14

Abstract excerpt

<h4>Background</h4> Impaired brain glucose metabolism is a preclinical feature of neurodegenerative diseases such as Alzheimer’s disease (AD). Infections may promote AD-related pathology. Therefore, we investigated the interplay between infections and APOE4 , a strong genetic risk factor for AD. <h4>Methods</h4> We analyzed data on 1,509 participants in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) databa...

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Literature Corpus work: 2ef030cc-7f38-5562-9a34-c400905cad3f
DOI: 10.1101/2024.09.13.24313582

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