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Article

Kainic Acid Pig Model of Hippocampal Epilepsy

2025-01-22

Abstract excerpt

Translational large-animal models that can accommodate human-scale implantable devices are essential for advancing neuromodulation therapies in epilepsy. This study establishes a kainic acid (KA)-induced porcine model of mesial temporal lobe epilepsy (mTLE) using clinical imaging, stereotactic surgery, and a fully implantable neural stimulation and recording (INSR) device designed for humans. Seven pigs (six KA-tr...

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Literature Corpus work
2eeeda75-08f7-5ed1-80d5-44e7105d2848
DOI
10.1101/2025.01.22.634312
Open publication

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Kainic Acid Pig Model of Hippocampal EpilepsyDOI 10.1101/2025.01.22.634312
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