Article

Optimal AAV capsid/promoter combinations to target specific cell types in the common marmoset cerebral cortex

2024-05-10

Abstract excerpt

To achieve cell type-specific gene expression, using target cell-tropic AAV capsids is advantageous. However, their tropism across brain cell types remains unexplored in non-human primates. We assessed the tropism of nine AAV serotype capsids (AAV1, 2, 5, 6, 7, 8, 9, rh.10 (rh10), and DJ) on marmoset cerebral cortical cell types. Marmoset cerebral cortex was injected with different serotype AAVs expressing enhance...

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Identifiers and source

Literature Corpus work: 2ee155db-cf51-56ef-b736-f4f6c7203c45
DOI: 10.1101/2024.05.09.593444

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