Article

Genetic and Cortical Cell-Type Liability Architecture of Autism

2025-12-12

Abstract excerpt

Autism Spectrum Disorders (ASD) can result from rare genetic variants interfering with brain development. Whether their effects converge on specific cortical cell types remains unresolved. Previous studies have focused on a narrow set of high-confidence ASD (hcASD) genes, which were enriched in neuronal cell types during prenatal development. By contrast, studies of postnatal cerebral cortex have repeatedly associ...

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Literature Corpus work: c33dd746-f89f-5e1e-bbd1-2772c7f7cfc9
DOI: 10.64898/2025.12.10.693473

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