Article

Expression weighted cell type enrichments reveal genetic and cellular nature of major brain disorders

2015-11-23

Abstract excerpt

The cell types that trigger the primary pathology in many brain diseases remain largely unknown. One route to understanding the primary pathological cell type for a particular disease is to identify the cells expressing susceptibility genes. Although this is straightforward for monogenic conditions where the causative mutation may alter expression of a cell type specific marker, methods are required for the common...

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Literature Corpus work: 3db96f9c-d087-5899-9f53-faa20f96a3f0
DOI: 10.1101/032680

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