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Proteomic Signatures of Hepatitis B Virus Mutations Reveal Genotype-Specific Host Responses and Biomarker Candidates

2025-09-09

Abstract excerpt

Hepatitis B virus (HBV) remains a global health challenge, with viral genetic heterogeneity and mutation-driven resistance complicating treatment outcomes. While previous genomic and transcriptomic studies have characterized HBV mutations, the proteomic consequences of these variants remain underexplored. In this study, we applied liquid chromatography– mass spectrometry (LC–MS)–based proteomics and systems biolog...

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Literature Corpus work
2ea13315-0586-53b4-be96-bb63b6dd886f
DOI
10.1101/2025.09.04.674240
Open publication

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Proteomic Signatures of Hepatitis B Virus Mutations Reveal Genotype-Specific Host Responses and Biomarker CandidatesDOI 10.1101/2025.09.04.674240
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