Hepatitis B Virus Genomic Variability & HBV-Related Disease Outcomes: A Molecular Epidemiology Perspective.

doi:10.1002/jmv.70760

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Article

Hepatitis B Virus Genomic Variability & HBV-Related Disease Outcomes: A Molecular Epidemiology Perspective.

Journal of medical virology - 1 Dec 2025

Bousali Maria, Papatheodoridis George, Bletsa Magdalini, Paraskevis Dimitrios, Karamitros Timokratis

Abstract excerpt

HBV infection remains a major global health challenge, characterized by diverse genotypes with distinct geographical distributions and clinical outcomes. Comprehensive analysis of HBV genomic variability and its association with disease progression is essential for improving clinical management and public health strategies. This study aimed to systematically investigate HBV genotype, subgenotype, phylogenetic...

Topics

Humans
Hepatitis B virus
Genotype
Molecular Epidemiology
Phylogeny
Genome, Viral
Genetic Variation
Mutation
Male
Hepatitis B
Carcinoma, Hepatocellular
Female
Liver Neoplasms
Middle Aged
Hepatitis B, Chronic
Adult

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PMID: 41424412
DOI: 10.1002/jmv.70760
PMCID: PMC12720221

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