Article

Network-based Computational Drug Combination Prediction

2016-04-16

Abstract excerpt

Cancers are complex diseases that are regulated by multiple signaling pathways. Patients often acquire resistance to single drug treatment. Use of drug combinations that target multiple parallel pathways is a promising strategy to reduce the drug resistance. Pharmacogenomics big data are being generated to uncover complex signaling mechanisms of cancers and correlate cancer-specific signaling with diverse drug res...

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Literature Corpus work: b0b51225-880b-58a0-899f-337035ad1b0d
DOI: 10.1101/049015

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