Article

African Ancestry GWAS of Dementia in a Large Military Cohort Identifies Significant Risk Loci

2022-05-26

Abstract excerpt

We conducted the largest genome-wide association study (GWAS) of Alzheimer’s disease and related dementia (ADRD) in individuals of African-ancestry (AFR) to date using participants from the Million Veteran Program (MVP; 4,012 ADRD cases and 18,435 controls). A proxy GWAS based on survey-reported parental dementia (n=6,641 proxy cases, 45,970 controls) was also performed. The MVP AFR ADRD GWAS and proxy GWAS result...

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Literature Corpus work: 2e870f65-8149-58fc-9a12-3ad3538e5307
DOI: 10.1101/2022.05.25.22275553

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