Article

Methyl donor deficient diets cause distinct alterations in lipid metabolism but are poorly representative of human NAFLD

2017-07-11

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD) is a global health issue. Dietary methyl donor restriction is used to induce a NAFLD/non-alcoholic steatohepatitis (NASH) phenotype in rodents, however the extent to which this model reflects human NAFLD remains incompletely understood. To address this, we undertook hepatic transcriptional profiling of methyl donor restricted rodents and compared these to published human N...

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Literature Corpus work: 2df2e5e2-af63-5019-8e45-3077db4ceedc
DOI: 10.1101/162131

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