Article

CDR3 and V- genes show distinct reconstitution patterns in T-cell repertoire post allogeneic bone marrow transplantation

2020-03-06

Abstract excerpt

<h4>Background</h4> Restoration of T-cell repertoire diversity after allogeneic bone marrow transplantation (allo-BMT) is crucial for immune recovery. T-cell diversity is produced by rearrangements of germline gene segments (V (D) and J) of the T-cell receptor (TCR) α and β chains, and selection induced by binding of TCRs to MHC-peptide complexes. This diversity can be measured by many measures. We here focus on...

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Literature Corpus work: 2df014a0-a14e-5b64-bfdd-9e4028ee9b6f
DOI: 10.1101/2020.03.05.977900

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