Article
Genetic T-cell receptor diversity at 1 year following allogeneic hematopoietic stem cell transplantation.
Leukemia - 1 May 2020
Buhler Stéphane, Bettens Florence, Dantin Carole, Ferrari-Lacraz Sylvie, Ansari Marc, Mamez Anne-Claire, Masouridi-Levrat Stavroula, Chalandon Yves, Villard Jean
Abstract excerpt
After allogeneic hematopoietic stem cell transplantation (HSCT), immune reconstitution leads to the development of a new T-cell repertoire. Immune reconstitution could be influenced by events such as conditioning, infections, and graft versus host disease (GVHD). Factors influencing the TCR diversity are of great interest to fine-tune the strategy for donor selection and to optimize standard of care. In this...
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