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Article

Insights into cytomegalovirus-associated T cell receptors in recipients following allogeneic hematopoietic stem cell transplantation.

Virology journal - 30 Sept 2024

Xia Jintao, Xiao Yingjun, Gui Genyong, Gong Shengnan, Wang Huiqi, Li Xuejie, Yan Ren, Fan Jun

Abstract excerpt

BACKGROUND: Cytomegalovirus (CMV) reactivation is a serious problem in recipients of allogeneic hematopoietic stem cell transplantation. Long-term latency depends on specific T cell immune reconstitution, which identifies various pathogens by T cell receptors (TCRs). However, the mechanisms underlying the selection of CMV-specific TCRs in recipients after transplantation remain unclear. METHODS: Using...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39350155
DOI: 10.1186/s12985-024-02511-x
PMCID: PMC11443867

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