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Quantitative characterization of T-cell repertoire in allogeneic hematopoietic stem cell transplant recipients

8 Jun 2015

Abstract excerpt

Allogeneic hematopoietic stem cell transplantation (HSCT) is one of curative treatment options for patients with hematologic malignancies. Although GVHD mediated by the donor's T lymphocytes remains the most challenging toxicity of allo-HSCT, graft-versus-leukemia (GVL) effect targeting leukemic cells, has an important role in affecting the overall outcome of patients with AML. Here we comprehensively...

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PMID: 26052909
DOI: 10.1038/bmt.2015.133

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