Article

GDNF family receptor alpha-like (GFRAL) expression is restricted to the caudal brainstem

2024-09-19

Abstract excerpt

The TGF-β cytokine, growth differentiation factor 15 (GDF15) is a critical mediator of the physiologic response to a range of cellular stresses. While circulating levels of GDF15 are normally very low, these levels increase substantially under a number of acute and chronic pathogenic states including mycotoxin exposure, infection and cancer. GDF15 controls a range of physiologic outputs including reduced appetite,...

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Literature Corpus work: 2de775fa-6440-5b6e-a00d-478860013fec
DOI: 10.1101/2024.09.19.613956

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