Article

Computational Modeling of Functionalized Graphene Quantum Dots Binding to Tau Fibrils in Alzheimer’s Disease

2026-07-30

Abstract excerpt

The aggregation of Tau protein into straight filaments (SFs) and paired helical filaments (PHFs) is central to Alzheimer’s disease (AD) pathology and a key target for therapeutic inhibition. Graphene quantum dots (GQDs) are biocompatible nanomaterials that have shown promise in inhibiting amyloidogenic protein aggregation across related neurological pathologies. The effect of GQD functionalization on interactions...

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Literature Corpus work: 2daa1020-cba4-5f85-ba94-556dadd2ef6c
DOI: 10.64898/2026.07.29.741532

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