Integrative epigenetics and transcriptomics identify aging genes in human blood

Abstract excerpt

Recent epigenome-wide studies have identified a large number of genomic regions that consistently exhibit changes in their methylation status with aging across diverse populations, but the functional consequences of these changes are largely unknown. On the other hand, transcriptomic changes are more easily interpreted than epigenetic alterations, but previously identified age-related gene expression changes have...

Topics

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• Aging
• DNA
• Follow-Up Studies
• Gene Expression
• Gene Expression Profiling
• Gene Regulatory Networks
• Time Factors
• Transcriptome

Identifiers and source

Literature Corpus work

839bc4b6-7c73-5725-bb64-07e8505b241d

DOI

10.1101/2024.05.30.596713