Article

Endogenous insulin contributes to pancreatic cancer development

2019-01-24

Abstract excerpt

Obesity and early-stage type 2 diabetes (T2D) increase the risk for many cancers, including pancreatic ductal adenocarcinoma (PDAC). The mechanisms linking obesity and T2D to cancer have not been established, preventing targeted interventions. Arguments have been made that hyperinsulinemia, hyperglycemia, or inflammation could drive cancer initiation and/or progression 1 . Hyperinsulinemia is a cardinal feature o...

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Literature Corpus work: 2da29c81-7454-55dd-baaf-8120fd72d1c1
DOI: 10.1101/530097

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