Article
The Impact of obesity and diabetes mellitus on pancreatic cancer: Molecular mechanisms and clinical perspectives.
Journal of cellular and molecular medicine - 1 Jul 2020
Quoc Lam Bao, Shrivastava Sushant K, Shrivastava Anju, Shankar Sharmila, Srivastava Rakesh K
Abstract excerpt
The incidence of obesity and type 2 diabetes (T2DM) in the Western world has increased dramatically during the recent decades. According to the American Cancer Society, pancreatic cancer (PC) is the fourth leading cause of cancer-related death in the United States. The relationship among obesity, T2DM and PC is complex. Due to increase in obesity, diabetes, alcohol consumption and sedentary lifestyle, the...
Topics
- Animals
- Biomarkers
- Cellular Microenvironment
- Diabetes Mellitus, Type 2
- Disease Management
- Disease Susceptibility
- Humans
- Hypoglycemic Agents
- Mutation
- Obesity
- Pancreatic Neoplasms