Article

Motifs of the C-terminal Domain of MCM9 Direct Localization to Sites of Mitomycin-C Damage for RAD51 Recruitment

2020-07-29

Abstract excerpt

The MCM8/9 complex is implicated in aiding fork progression and facilitating homologous recombination (HR) in response to several DNA damage agents. MCM9 itself is an outlier within the MCM family containing a long C-terminal extension (CTE) comprising 42% of the total length, but with no known functional components and high predicted disorder. In this report, we identify and characterize two unique motifs within...

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Literature Corpus work: 2d9c7444-cf39-525e-83e6-ee251f454ba0
DOI: 10.1101/2020.07.29.227678

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