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Article

Region-specific metabolic alterations in the brain of the APP/PS1 transgenic mice of Alzheimer's disease.

Biochimica et biophysica acta - 1 Dec 2014

González-Domínguez Raúl, García-Barrera Tamara, Vitorica Javier, Gómez-Ariza José Luis

Abstract excerpt

Alzheimer's disease (AD) is the most common neurodegenerative disorder worldwide, but its etiology is still not completely understood. The identification of underlying pathological mechanisms is becoming increasingly important for the discovery of biomarkers and therapies, for which metabolomics presents a great potential. In this work, we studied metabolic alterations in different brain regions of the APP/PS1...

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PMID: 25281826
DOI: 10.1016/j.bbadis.2014.09.014

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APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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