Article

SARS-CoV-2 infection activates inflammatory macrophages in vascular immune organoids

2024-03-21

Abstract excerpt

SARS-CoV-2 provokes devastating tissue damage by cytokine release syndrome and leads to multi-organ failure. Modeling the process of immune cell activation and subsequent tissue damage is a significant task. Organoids from human tissues advanced our understanding of SARS-CoV-2 infection mechanisms though, they are missing crucial components: immune cells and endothelial cells. This study aims to generate organoids...

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Literature Corpus work: 2d6d4143-5483-5b35-8ffc-b31dd7bb8c24
DOI: 10.1101/2024.03.20.585837

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