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The use of human iPSC‐derived alveolar organoids to explore SARS‐CoV‐2 variant infections and host responses

1 Apr 2024

Abstract excerpt

Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) primarily targets the respiratory system. Physiologically relevant human lung models are indispensable to investigate virus-induced host response and disease pathogenesis. In this study, we generated human induced pluripotent stem cell (iPSC)-derived alveolar organoids (AOs) using an established protocol that recapitulates the sequential steps...

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PMID: 38572923
DOI: 10.1002/jmv.29579

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