Article

miR-1, miR-133a, miR-29b and Skeletal Muscle Fibrosis in Chronic Limb-Threatening Ischaemia.

2024-04-19

Abstract excerpt

<title>Abstract</title> <p>Chronic limb-threatening ischaemia (CLTI), the most severe manifestation of peripheral arterial disease (PAD), is associated with a poor prognosis and high amputation rates. Despite novel therapeutics approaches being investigated, no significant clinical benefits habe been observed yet. Understanding the molecular pathways of skeletal muscle dysfunction in CLTI is crucial for designing...

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Literature Corpus work: 5b77a221-0983-50a4-b613-4acbde4bb800
DOI: 10.21203/rs.3.rs-4242453/v1

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