Article

Head and neck squamous cell carcinoma-derived extracellular vesicles mediate Ca²⁺-dependent platelet activation and aggregation through tissue factor

2025-04-30

Abstract excerpt

<title>Abstract</title> <p>Background Head and neck squamous cell carcinoma (HNSCC) is an aggressive malignancy, characterized by poor clinical outcomes, primarily driven by high rate of locoregional recurrence and metastasis. Extensive heterogeneity among the tumor cells as well as modulation of a highly immunosuppressive tumor microenvironment shape cancer progression. Shedding of extracellular vesicles (EVs)...

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Literature Corpus work: 3b1e3cfc-6c0c-5e91-9dca-75d769087b5f
DOI: 10.21203/rs.3.rs-6017719/v1

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