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Exosome-mediated miR-21 promotes angiogenesis within esophageal tumor microenvironment by activating PTEN/Akt signaling pathway in Vascular Endothelial Cells

2020-05-29

Abstract excerpt

<title>Abstract</title> <p>Background Angiogenesis, a pivotal component in the tumor microenvironment (TME), boosts tumor growth and metastasis. Cancer-derived exosomes, which have been widely reported to play a crucial role in the establishment of TME can be effective angiogenic modulators. We aim to investigate the contribution of microRNA-21 (miR-21) for angiogenesis which was packaged in cancer-derived exoso...

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Literature Corpus work
527a5266-8032-5be7-88fd-6dab0ed9f513
DOI
10.21203/rs.3.rs-31065/v1
Open publication

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Exosome-mediated miR-21 promotes angiogenesis within esophageal tumor microenvironment by activating PTEN/Akt signaling pathway in Vascular Endothelial CellsDOI 10.21203/rs.3.rs-31065/v1
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