Back to search

Article

A polygenic risk score improves the prediction of cardiovascular risk associated with obstructive sleep-apnea

2025-12-09

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Obstructive sleep apnea (OSA) carries increased cardiovascular (CV) risk. However, this risk is not fully captured by the apnea–hypopnea index (AHI). We investigated whether a validated coronary artery disease polygenic risk score (CAD-PRS) refines CV risk assessment in OSA. <h4>Methods</h4> We derived CAD-PRS using genome-wide genotyping data for 1,379 participants of th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
2c675539-e96a-5223-a5bc-bcc89225179f
DOI
10.64898/2025.12.08.25341829
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A polygenic risk score improves the prediction of cardiovascular risk associated with obstructive sleep-apneaDOI 10.64898/2025.12.08.25341829
Polygenic scores for obstructive sleep apnea based on BMI-adjusted and -unadjusted genetic associations reveal pathways contributing to cardiovascular diseaseSemantic proximity
Polygenic scores for obstructive sleep apnoea reveal pathways contributing to cardiovascular disease.Semantic proximity
Combining polygenic and clinical risk scores in atrial fibrillation risk prediction: Implications for population screening.Semantic proximity
Polygenic scores for obstructive sleep apnoea reveal pathways contributing to cardiovascular diseaseSemantic proximity
Combining European and U.S. risk prediction models with polygenic risk scores to refine cardiovascular prevention: the CoLaus|PsyCoLaus StudySemantic proximity
Polygenic risk, lifestyle, and cardiovascular mortality: a prospective population-based UK Biobank studySemantic proximity
Integrating Phenotypic Information of Obstructive Sleep Apnea and Deep Representation of Sleep-Event Sequences for Cardiovascular Risk PredictionSemantic proximity
Polygenic Risk, Lifestyle, and Cardiovascular Mortality: A Prospective UK Biobank StudySemantic proximity
A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study.Semantic proximity
Integrating phenotypic information of obstructive sleep apnea and deep representation of sleep-event sequences for cardiovascular risk prediction.Semantic proximity
Integrated Polygenic Tool Substantially Enhances Coronary Artery Disease Prediction.Semantic proximity
Pathway-specific Polygenic Risk Scores (PRS) identify OSA-related pathways differentially moderating genetic susceptibility to CADSemantic proximity
Select a neighboring publication to make it the new centre.