Article

A fast and efficient model for real-time anti-tumor drug efficacy test in the clinical setting based on patient-derived tumor xenograft

2021-05-17

Abstract excerpt

Drug response rates in cancer therapies are frequently unsatisfactory (first-line 30-40%, subsequent-line ~10% or less). The mouse model, patient-derived tumor xenograft (PDTX), can help promote drug effective rate to over 80% by precisely electing efficacious agents. However, the low engraftment rates, extended testing cycle, and high cost limit its utilization in the clinical setting. A novel method, FastPDTX, w...

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Literature Corpus work: 2c512949-1dc6-5d13-90e0-1afea5b50484
DOI: 10.21203/rs.3.rs-453208/v1

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