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Article

Zebrafish patient-derived xenografts accurately and quickly reproduce treatment outcomes in non-small cell lung cancer patients.

Experimental biology and medicine (Maywood, N.J.) - 1 Feb 2023

Hua Xin, Wu Xiaodi, Xu Ke, Zhan Ping, Liu Hongbing, Zhang Fang, Lv Tangfeng, Song Yong

Abstract excerpt

Zebrafish patient-derived xenograft (zPDX) models have shown great potential in predicting the short-term treatment response in various types of tumor cases. However, few studies have used zPDX models for drug screening in non-small cell lung cancer (NSCLC). We aimed to compare the treatment responses of patients with NSCLC with those of the corresponding zPDX models. Tumor cells were obtained from pleural fluid...

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Identifiers

PMID: 36533580
DOI: 10.1177/15353702221142612
PMCID: PMC10159519

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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