Article

A multicenter clinical study: personalized medication for advanced gastrointestinal carcinomas with the guidance of Patient-Derived Tumor Xenograft (PDTX)

2021-02-19

Abstract excerpt

<title>Abstract</title> <p>Background: Establish patient-derived tumor xenograft (PDTX) from advanced GICs and assess the clinical value and applicability of PDTX for the treatment of advanced GICs. <h4>Method:</h4> Patients with advanced GICs were enrolled in a registered multi-center clinical study (ChiCTR-OOC-17012731). The performance of PDTX were evaluated includes: analyzing factors that affect the engraftm...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 85aa65a4-d89f-5a50-8d13-0613e09f616b
DOI: 10.21203/rs.3.rs-212867/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A multicenter clinical study: personalized medication for advanced gastrointestinal carcinomas with the guidance of Patient-Derived Tumor Xenograft (PDTX)DOI 10.21203/rs.3.rs-212867/v1Read

A fast and efficient model for real-time anti-tumor drug efficacy test in the clinical setting based on patient-derived tumor xenograftSemantic proximity Read

Xenograft and organoid models in developing precision medicine for gastric cancer (Review)Semantic proximity Read

Establishment and its Utility of a Patient-Derived Cell Xenografts (PDCX) Model with Cryopreserved Cancer Cells from Human TumorSemantic proximity Read

Challenges and Prospects of Patient-Derived Xenografts for Cancer ResearchSemantic proximity Read

Establishment and Drug Screening of Patient-Derived Extrahepatic Biliary Tract Carcinoma OrganoidsSemantic proximity Read

Patient-derived xenograft (PDX) models: characteristics and points to consider for the process of establishmentSemantic proximity Read

Patient-Derived Gastric Carcinoma Xenograft Mouse Models Faithfully Represent Human Tumor Molecular DiversitySemantic proximity Read

Combining molecular characteristics and therapeutic analysis of PDOs predict clinical responses and guide PDAC personalized treatmentSemantic proximity Read

Technological advances in clinical individualized medication for cancer therapy: from genes to whole organismSemantic proximity Read

Colorectal Cancer Patient‐Derived 2D and 3D Models Efficiently Recapitulate Inter‐ and Intratumoral HeterogeneitySemantic proximity Read

A Chemosensitivity Study of Colorectal Cancer Using Xenografts of Patient-Derived Tumor-Initiating Cells.Semantic proximity Read

Utility of patient-derived xenografts to evaluate drug sensitivity and select optimal treatments for individual non-small-cell lung cancer patientsSemantic proximity Read