Substantial Deceleration of Adaptation of HIV-1 Within 1,500 Generations in an Experimental Evolution: A Genomic Perspective

Abstract excerpt

Numerous experimental evolution studies have suggested that adaptation rate of microbial populations evolving in stable environments decline over time. Despite the generality of this phenomenon across different domains of life, the timing and magnitude of decline in adaptation can vary greatly based on the idiosyncrasies of the biological system. To investigate the characteristics of adaptation deceleration in a f...

Topics

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• Adaptation, Biological
• Drug Resistance
• Environment
• Evolution, Molecular
• HIV Infections
• Mutation
• Selection, Genetic
• Sindbis Virus

Identifiers and source

Literature Corpus work

2be1841c-b2f1-58c3-b8cf-1841bb8172d0

DOI

10.64898/2026.02.04.700995