Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Different trajectories of parallel evolution during viral adaptation.

Science (New York, N.Y.) - 16 Jul 1999

Wichman H A, Badgett M R, Scott L A, Boulianne C M, Bull J J

Abstract excerpt

The molecular basis of adaptation is a major focus of evolutionary biology, yet the dynamic process of adaptation has been explored only piecemeal. Experimental evolution of two bacteriophage lines under strong selection led to over a dozen nucleotide changes genomewide in each replicate. At least 96 percent of the amino acid substitutions appeared to be adaptive, and half the changes in one line also occurred in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Bacteriophage phi X 174
Share to Genome, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Salmonella typhimurium

Share to Sequence Deletion

Share to Viral Plaque Assay

Share to Viral Proteins

Share to Virus Replication

Source

Identifiers

PMID: 10411508
DOI: 10.1126/science.285.5426.422

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Different trajectories of parallel evolution during viral adaptation.PMID 10411508Read ↗

Mutation-Driven Parallel Evolution during Viral Adaptation.Semantic proximity Read ↗

Parallel molecular evolution and adaptation in viruses.Semantic proximity Read ↗

Genomewide patterns of substitution in adaptively evolving populations of the RNA bacteriophage MS2.Semantic proximity Read ↗

Mutational effects and population dynamics during viral adaptation challenge current models.Semantic proximity Read ↗

Viral host-adaptation: insights from evolution experiments with phages.Semantic proximity Read ↗

Evolutionary reversals during viral adaptation to alternating hosts.Semantic proximity Read ↗

Molecular adaptations during viral epidemicsSemantic proximity Read ↗

Dynamics of molecular evolution in RNA virus populations depend on sudden versus gradual environmental change.Semantic proximity Read ↗

Population size changes and selection drive patterns of parallel evolution in a host-virus system.Semantic proximity Read ↗

Substantial Deceleration of Adaptation of HIV-1 Within 1,500 Generations in an Experimental Evolution: A Genomic PerspectiveSemantic proximity Read ↗

Parallel genetic evolution within and between bacteriophage species of varying degrees of divergence.Semantic proximity Read ↗

Adaptive value of high mutation rates of RNA viruses: separating causes from consequences.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.