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Article

Adaptation in the env gene of HIV-1 and evolutionary theories of disease progression.

Molecular biology and evolution - 1 Aug 2003

Williamson Scott

Abstract excerpt

The exact mechanisms by which HIV overwhelms the immune system remain poorly understood. Among the several explanations of HIV disease progression, most include adaptation of the viral genome to the host environment as a causal factor. Therefore, quantifying the rate and pattern of adaptive evolution within infected patients is critical to understanding the development of AIDS. Using sequence data from infected...

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Share to Disease Progression
Share to Evolution, Molecular
Share to Genes, env

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Envelope Protein gp120

Share to HIV Infections

Share to Phylogeny

Share to Polymorphism, Single-Stranded Conformational

Source

Identifiers

PMID: 12777505
DOI: 10.1093/molbev/msg144

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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