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Article

Long-term experimental evolution of HIV-1 reveals effects of environment and mutational history.

PLoS biology - 1 Dec 2020

Bons Eva, Leemann Christine, Metzner Karin J, Regoes Roland R

Abstract excerpt

An often-returning question for not only HIV-1, but also other organisms, is how predictable evolutionary paths are. The environment, mutational history, and random processes can all impact the exact evolutionary paths, but to which extent these factors contribute to the evolutionary dynamics of a particular system is an open question. Especially in a virus like HIV-1, with a large mutation rate and large...

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Identifiers

PMID: 33370289
DOI: 10.1371/journal.pbio.3001010
PMCID: PMC7793244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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