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Article

Loss and recovery of genetic diversity in adapting populations of HIV.

PLoS genetics - 1 Jan 2014

Pennings Pleuni S, Kryazhimskiy Sergey, Wakeley John

Abstract excerpt

The evolution of drug resistance in HIV occurs by the fixation of specific, well-known, drug-resistance mutations, but the underlying population genetic processes are not well understood. By analyzing within-patient longitudinal sequence data, we make four observations that shed a light on the underlying processes and allow us to infer the short-term effective population size of the viral population in a patient....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24465214
DOI: 10.1371/journal.pgen.1004000
PMCID: PMC3900388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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