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Trans-ethnic eQTL meta-analysis of human brain reveals regulatory architecture and candidate causal variants for brain-related traits

2021-01-30

Abstract excerpt

While large-scale genome-wide association studies (GWAS) have identified hundreds of loci associated with neuropsychiatric and neurodegenerative traits, identifying the variants, genes and molecular mechanisms underlying these traits remains challenging. Integrating GWAS results with expression quantitative trait loci (eQTLs) and identifying shared genetic architecture has been widely adopted to nominate genes and...

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Literature Corpus work
2bc52547-0afc-573b-a8e2-335023c7d73a
DOI
10.1101/2021.01.25.21250099
Open publication

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Trans-ethnic eQTL meta-analysis of human brain reveals regulatory architecture and candidate causal variants for brain-related traitsDOI 10.1101/2021.01.25.21250099
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