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Synaptosome microRNAs regulate synapse functions in Alzheimer’s disease

2021-12-18

Abstract excerpt

MicroRNAs (miRNAs) are found in nerve terminals, synaptic vesicles, and synaptosomes, but it is unclear whether synaptic and cytosolic miRNA populations differ in Alzheimer’s disease (AD) or if synaptosomal miRNAs affect AD synapse activity. To address these questions, we generated synaptosomes and cytosolic fractions from postmortem brains of AD and unaffected control (UC) samples and analyzed them using a global...

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Literature Corpus work
2bb2bf88-9b59-5f6e-8325-aa3fdb72139d
DOI
10.1101/2021.12.15.472852
Open publication

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Synaptosome microRNAs regulate synapse functions in Alzheimer’s diseaseDOI 10.1101/2021.12.15.472852
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