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microRNAs as Early Biomarkers of Alzheimer’s Disease: A Synaptic Perspective

9 Jan 2021

Abstract excerpt

Pathogenic processes underlying Alzheimer's disease (AD) affect synaptic function from initial asymptomatic stages, long time before the onset of cognitive decline and neurodegeneration. Therefore, reliable biomarkers enabling early AD diagnosis and prognosis are needed to maximize the time window for therapeutic interventions. MicroRNAs (miRNAs) have recently emerged as promising cost-effective and non-invasive...

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PMID: 33435363
DOI: 10.3390/cells10010113

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