Article

MicroRNA-502-3p modulates the GABA A subunits, synaptic proteins and mitochondrial morphology in hippocampal neurons

2025-01-13

Abstract excerpt

<h4>ABSTRACT</h4> MicroRNA-502-3p (MiR-502-3p), a synapse enriched miRNA is considerably implicated in Alzheimer’s disease (AD). Our previous study found the high expression level of miR-502-3p in AD synapses relative to controls. Further, miR-502-3p was found to modulate the GABAergic synapse function via modulating the GABA A receptor subunit α-1 (GABRA1) protein. The current study is attempted to examine the i...

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Literature Corpus work: cbe59995-78fc-58c8-a950-4676096d1d07
DOI: 10.1101/2025.01.09.632229

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