Article
Subcellular targeting of Salmonella virulence proteins by host-mediated S-palmitoylation.
Cell host & microbe - 21 Jul 2011
Hicks Stuart W, Charron Guillaume, Hang Howard C, Galán Jorge E
Abstract excerpt
Several pathogenic bacteria utilize type III secretion systems (TTSS) to deliver into host cells bacterial virulence proteins with the capacity to modulate a variety of cellular pathways. Once delivered into host cells, the accurate targeting of bacterial effectors to specific locations is critical for their proper function. However, little is known about the mechanisms these virulence effectors use to reach...
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