Article

Human SARS-CoV-2 has evolved to reduce CG dinucleotide in its open reading frames

2020-04-02

Abstract excerpt

The causative agent of COVID-19 is a severe acute respiratory syndrome-related coronavirus which has been officially named SARS-CoV-2. Here we report the discovery of extremely low CG abundance in its open reading frames. We found that CG reduction in SARS-CoV-2 is achieved mainly through mutating C/G into A/T, and CG is the best target for mutation. In view of energy usage, a coronavirus with low CG abundance has...

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Literature Corpus work: 2b2906cb-b072-5cb5-8af7-f10765342e8d
DOI: 10.21203/rs.3.rs-21003/v1

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