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Human SARS-CoV-2 has evolved to increase U content and reduce genome size.

International journal of biological macromolecules - 15 Apr 2022

Wang Yong, Chen Xin-Yu, Yang Liu, Yao Qin, Chen K P

Abstract excerpt

Infections caused by SARS-CoV-2 have brought great harm to human health. After transmission for over two years, SARS-CoV-2 has diverged greatly and formed dozens of different lineages. Understanding the trend of its genome evolution could help foresee difficulties in controlling transmission of the virus. In this study, we conducted an extensive monthly survey and in-depth analysis on variations of nucleotide,...

Topics

Base Composition
Base Sequence
COVID-19
China
Codon
Evolution, Molecular
Genome
Genome Size
Genome, Viral
Humans
Mutation
Phylogeny

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

SARS-CoV-2

Uracil

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Identifiers

PMID: 35149094
DOI: 10.1016/j.ijbiomac.2022.02.034
PMCID: PMC8824384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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