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Whole genome sequencing-based detection of extensively drug-resistant tuberculosis from Ethiopia

7 Dec 2025

Abstract excerpt

Rapid and accurate detection of extensively drug-resistant tuberculosis is crucial for effective intervention. Next-generation sequencing technologies have been recommended to rapidly and accurately detect resistance to second-line anti-TB drugs. We deployed whole-genome sequencing to detect mutations associated with drug resistance in pre-extensively drug-resistant tuberculosis and extensively drug-resistant...

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PMID: 41354901
DOI: 10.1038/s43856-025-01271-1

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