Article
Exploration of the diversity of multi-drug resistant Mycobacterium tuberculosis complex in Lagos, Nigeria using WGS: Distribution of lineages, drug resistance patterns and genetic mutations.
Tuberculosis (Edinburgh, Scotland) - 1 May 2023
Noorizhab Mohd Nur Fakhruzzaman, Zainal Abidin Norzuliana, Teh Lay Kek, Tang Thean Hock, Onyejepu Nneka, Kunle-Ope Chioma, Tochukwu Nwanneka E, Sheshi Michael A, Nwafor Timothy, Akinwale Olaoluwa P, Ismail Ahmad Izuanuddin, Nor Norazmi Mohd, Salleh Mohd Zaki
Abstract excerpt
Multidrug-resistant (MDR) or extensively drug-resistant (XDR) Tuberculosis (TB) is a major challenge to global TB control. Therefore, accurate tracing of in-country MDR-TB transmission are crucial for the development of optimal TB management strategies. This study aimed to investigate the diversity of MTBC in Nigeria. The lineage and drug-resistance patterns of the clinical MTBC isolates of TB patients in...
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