Article

Artery-on-chip demonstrates smooth muscle function comparable to both healthy and diseased living tissues

2025-03-11

Abstract excerpt

<h4>ABSTRACT</h4> Arterial diseases affect the mechanical properties of blood vessels, which then alter their function via complex mechanisms. To develop and test effective treatments, microphysiological systems replicating the function and mechanics of a human artery are needed. Here, we establish an artery-on-chip (ARTOC) using vascular derivatives of human induced pluripotent stem cells (iPSCs) cultured with p...

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Literature Corpus work: 2a45e8bf-23b8-5311-8c1d-169170ed2fd5
DOI: 10.1101/2025.03.06.641764

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