Article

A novel xenograft model reveals invasive mesenchymal transition and ineffective angiogenic response during anti-angiogenic therapy resistance

2018-02-28

Abstract excerpt

<h4>ABSTRACT</h4> Bevacizumab treatment of glioblastoma is limited by transient responses and acquired resistance. Because of the lengthy duration of treatment that can precede resistance in patients, in order to study changes underlying the evolution of bevacizumab resistance, we created a novel multigenerational xenograft model of acquired bevacizumab resistance. Glioblastoma xenografts were treated with bevaci...

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Literature Corpus work: 2a247c85-225e-533c-bcef-9932c6eaae29
DOI: 10.1101/272328

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