Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures

11 Apr 2023

Abstract excerpt

Glioblastoma (GBM) heterogeneity, aggressiveness and infiltrative growth drastically limit success of current standard of care drugs and efficacy of various new therapeutic approaches. There is a need for new therapies and models reflecting the complex biology of these tumors to analyze the molecular mechanisms of tumor formation and resistance, as well as to identify new therapeutic targets. We established and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cancer, Hypoxia, and Metabolism
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37114125
DOI: 10.3389/fonc.2023.1129627

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signaturesPMID 37114125Read ↗

Genomic and Phenotypic Characterization of a Broad Panel of Patient-Derived Xenografts Reflects the Diversity of Glioblastoma.Semantic proximity Read ↗

Emerging concepts in glioma biology: implications for clinical protocols and rational treatment strategies.Semantic proximity Read ↗

Glioblastoma Standard of Care: Effects on Tumor Evolution and Reverse Translation in Preclinical ModelsSemantic proximity Read ↗

Glioblastoma Standard of Care: Effects on Tumor Evolution and Reverse Translation in Preclinical ModelsSemantic proximity Read ↗

Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicineSemantic proximity Read ↗

Therapeutic Targets in Glioblastoma: Molecular Pathways, Emerging Strategies, and Future DirectionsSemantic proximity Read ↗

Glioblastoma preclinical models: Strengths and weaknessesSemantic proximity Read ↗

Generation of Glioblastoma Patient-Derived Intracranial Xenografts for Preclinical StudiesSemantic proximity Read ↗

Patient-derived tumor organoids mimic treatment-induced DNA damage response in glioblastomaSemantic proximity Read ↗

Optimized creation of glioblastoma patient derived xenografts for use in preclinical studies.Semantic proximity Read ↗

A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma.Semantic proximity Read ↗

Glioblastoma update: molecular biology, diagnosis, treatment, response assessment, and translational clinical trialsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.