Article

The Ets family transcription factor EHF suppresses senescence-associated inflammatory responses

2026-06-01

Abstract excerpt

Cellular senescence is a tumor-suppressive program characterized by irreversible growth arrest; however, senescent cells can also promote inflammation and alter the tumor microenvironment through the senescence-associated secretory phenotype (SASP). Although SASP induction is regulated by pathways such as p38/NF-κB/IκBζ, the mechanisms that restrain excessive or persistent SASP remain largely unknown. Here, we inv...

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Literature Corpus work: 2a037c78-2d60-5adf-8184-858351ef1742
DOI: 10.64898/2026.05.31.728776

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